Kisspeptin-54
Also known as Metastin, KP-54
One-dose burn-down
Half-life
28 min
Tmax
30 min
Typical dose
1 mcg
The 54-amino-acid kisspeptin studied as a physiologic trigger of GnRH/LH release in fertility research (a longer chain than kisspeptin-10).
Mechanism of action
Agonizes the KISS1R (GPR54) receptor on GnRH neurons, stimulating downstream LH/FSH secretion.
Research peptide — not approved. Plasma half-life ~28 min in human studies; trial dosing is typically weight-based.
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