Gonadorelin
Also known as GnRH, LHRH, Factrel
Gonadorelin is a lab version of the brain hormone GnRH that tells your pituitary to release LH and FSH — sometimes used alongside testosterone therapy to keep the testes active.
How one dose clears
modeled over ~6 half-lives- Half-life
- 18 min
- Time to peak (Tmax)
- 12 min
- Typical dose
- 100 mcg
Synthetic gonadotropin-releasing hormone (GnRH) used to stimulate pituitary LH/FSH release. Used off-label on TRT to maintain the HPTA, often as a shorter-acting alternative to HCG.
Mechanism of action
Activates pituitary GnRH receptors to trigger LH and FSH secretion, which in turn stimulate the gonads.
Prescription/research peptide. Plasma half-life is only minutes; the LH/FSH pulse it triggers far outlasts the drug in blood, so the burn-down understates its biological effect.
References
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