Reproductive

Oxytocin

Also known as Pitocin, Syntocinon

Oxytocin is the 'bonding' hormone — used in medicine for labor and breastfeeding, and (off-label, as a nasal spray) for mood and social connection.

One-dose burn-down
Half-life
6 min
Tmax
18 min
Typical dose
48 mcg

Neuropeptide hormone used clinically for labor/lactation (injectable) and used intranasally (off-label) for bonding, mood and libido.

Mechanism of action

Oxytocin receptor agonist — peripherally drives uterine contraction and milk ejection, centrally modulates social/affiliative behavior.

Prescription hormone (injectable). Very short half-life (1–6 min). Intranasal bioavailability is low (~1%) and CNS exposure is debated. Often dosed in IU (1 IU ≈ 2 mcg).

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FDA label (DailyMed)

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