Tirzepatide
Also known as Mounjaro, Zepbound
Tirzepatide (Mounjaro/Zepbound) is a weekly injection that hits two gut hormones at once (GIP and GLP-1), making it especially strong at cutting appetite and lowering blood sugar for diabetes and weight loss.
Dual GIP and GLP-1 receptor agonist for type 2 diabetes (Mounjaro) and weight management (Zepbound). Once-weekly subcutaneous injection.
Mechanism of action
Activates both GIP and GLP-1 receptors, amplifying glucose-dependent insulin secretion and appetite suppression with strong weight-loss effect.
Boxed warning for thyroid C-cell tumors. ~5-day half-life → ~4 weeks to steady state. Titrate monthly.
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