GIP / GLP-1 agonist

Tirzepatide reconstitution calculator

Also known as Mounjaro, Zepbound

Reconstitute Tirzepatide by adding bacteriostatic water to the vial, then draw your dose on a U-100 insulin syringe. The calculator is pre-filled with commonly-referenced vial sizes (10, 15, 30, 60 mg) and water volumes (1, 2, 3 mL) — every field is yours to override. Dual GIP/GLP-1 agonist dosed once weekly. Larger multi-dose vials are common, so concentration math matters most here.

New to this? How to use the calculator
  1. 1Enter what's on your vial. Type the peptide amount (mg) printed on the vial and the mL of bacteriostatic water you mixed in. Not sure how much water to add? Switch to the Solve: water tab and it tells you.
  2. 2Enter your dose — mind the unit. Type your target dose and pick mg or mcg with the toggle. This matters: 1 mg = 1000 mcg. GLP-1s (semaglutide, tirzepatide) are usually mg; most peptides (BPC-157, ipamorelin) are mcg.
  3. 3Read “Draw to … units”. The big number is how far to pull the plunger on a U-100 insulin syringe. Match it to the fill line on the syringe picture. The concentration and doses per vial are shown so a wrong answer looks wrong.

Three ways to use it: Solve: units (you have a dose, find the draw), Solve: water (you want a clean mark like 10 units, find the water), and Solve: dose (you drew some units, find the dose).

Full step-by-step guide

I have a vial, water and a dose — how many units do I draw?

02040Draw to 25 unitsU-100 · 50u max
Draw to
25 u
Concentration
10 mg/mL
Dose volume
0.25 mL
Doses / vial
4

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This tool computes volumes only — it does not recommend doses. Any pre-filled values are commonly-referenced examples to confirm with your provider. Always verify the concentration and draw against your own vial and syringe.

Tirzepatide concentration quick-reference

VialBAC waterConcentrationUnits for 2.5 mg
10 mg1 mL10 mg/mL25 u
10 mg2 mL5 mg/mL50 u
10 mg3 mL3.33 mg/mL75 u
15 mg1 mL15 mg/mL16.7 u
15 mg2 mL7.5 mg/mL33.3 u
15 mg3 mL5 mg/mL50 u
30 mg1 mL30 mg/mL8.33 u
30 mg2 mL15 mg/mL16.7 u
30 mg3 mL10 mg/mL25 u
60 mg1 mL60 mg/mL4.17 u
60 mg2 mL30 mg/mL8.33 u
60 mg3 mL20 mg/mL12.5 u

Example inputs for illustration. Confirm your actual dose with your provider.

Tirzepatide has a reported half-life of about 5.0 days. Track how much stays active between doses with a real pharmacokinetic burn-down.

Track Tirzepatide in PeptideBuddy

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