PeptideBuddy
GIP / GLP-1 agonist

Tirzepatide reconstitution calculator

Also known as Mounjaro, Zepbound

Reconstitute Tirzepatide by adding bacteriostatic water to the vial, then draw your dose on a U-100 insulin syringe. The calculator is pre-filled with commonly-referenced vial sizes (10, 15, 30, 60 mg) and water volumes (1, 2, 3 mL) — every field is yours to override. Dual GIP/GLP-1 agonist dosed once weekly. Larger multi-dose vials are common, so concentration math matters most here.

New to this? How to use the calculator
  1. 1Enter what's on your vial. Type the peptide amount (mg) printed on the vial and the mL of bacteriostatic water you mixed in. Not sure how much water to add? Switch to the Solve: water tab and it tells you.
  2. 2Enter your dose — mind the unit. Type your target dose and pick mg or mcg with the toggle. This matters: 1 mg = 1000 mcg. GLP-1s (semaglutide, tirzepatide) are usually mg; most peptides (BPC-157, ipamorelin) are mcg.
  3. 3Read “Draw to … units”. The big number is how far to pull the plunger on a U-100 insulin syringe. Match it to the fill line on the syringe picture. The concentration and doses per vial are shown so a wrong answer looks wrong.
Three ways to use it
  • Solve: units — you know the dose; find how far to draw.
  • Solve: water — you want a round mark like 10 units; find how much water to add.
  • Solve: dose — you already drew some units; find the dose that was.
Full step-by-step guide

I have a vial, water and a dose — how many units do I draw?

Target dose
Check the unit: 1 mg = 1000 mcg.
Syringe size
U-100 insulin syringe — 1 mL holds 100 units.
Draw to
25 units
02040Draw to 25 unitsU-100 · 50u max
Concentration
10 mg/mL
Volume per dose
0.25 mL
Doses per vial
4
A U-100 syringe is marked in whole units. The nearest mark is 25 units, which delivers 2.5 mg.

Easier-to-read mixes

4 doses per vial either way

Different amounts of water put the same dose on a rounder mark. Tap one to use that water amount.

Want this dose scheduled, checked off daily and tracked by half-life?

Track it for free

This tool computes volumes only — it does not recommend doses. Any pre-filled values are commonly referenced examples to confirm with your provider. Always check the concentration and draw against your own vial and syringe.

Tirzepatide concentration quick-reference

VialBAC waterConcentrationUnits for 2.5 mg
10 mg1 mL10 mg/mL25 units
10 mg2 mL5 mg/mL50 units
10 mg3 mL3.33 mg/mL75 units
15 mg1 mL15 mg/mL16.7 units
15 mg2 mL7.5 mg/mL33.3 units
15 mg3 mL5 mg/mL50 units
30 mg1 mL30 mg/mL8.33 units
30 mg2 mL15 mg/mL16.7 units
30 mg3 mL10 mg/mL25 units
60 mg1 mL60 mg/mL4.17 units
60 mg2 mL30 mg/mL8.33 units
60 mg3 mL20 mg/mL12.5 units

Example inputs for illustration. Confirm your actual dose with your provider.

Tirzepatide has a reported half-life of about 5.0 days. Track how much stays active between doses with a real pharmacokinetic burn-down.

Track Tirzepatide in PeptideBuddy

Embed this calculator

Drop the Tirzepatide calculator into your forum post or blog:

<iframe src="https://www.peptidebuddy.ai/embed/recon/tirzepatide" width="100%" height="640" style="border:1px solid #e2e8f0;border-radius:16px" title="Tirzepatide reconstitution calculator"></iframe>