Thymosin Beta-4
Also known as TB-4, Tβ4, RGN-352
Thymosin Beta-4 is the full natural repair peptide (TB-500 is a shorter fragment of it), studied for healing of tissue, heart, and nerves.
How one dose clears
modeled over ~6 half-lives- Half-life
- 2.0 h
- Reported range
- 30 min–2.0 h
- Time to peak (Tmax)
- 12 min
- Typical dose
- 5 mg
The full-length 43-amino-acid thymosin beta-4 peptide (vs the shorter TB-500 fragment) studied for tissue, cardiac and wound repair.
Mechanism of action
Actin-sequestering peptide that regulates the cytoskeleton, promoting cell migration, angiogenesis and tissue repair.
Research peptide — not approved. Human PK exists only for IV dosing (~0.5–2 h); subcutaneous half-life is an estimate.
References
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