B7-33
Also known as B7/8-33
B7-33 is an experimental peptide based on the hormone relaxin, studied for its potential to reduce fibrosis (scarring) in organs like the heart and lungs. Early-stage research only.
How one dose clears
modeled over ~6 half-lives- Half-life
- 18 min
- Time to peak (Tmax)
- 12 min
- Typical dose
- 100 mcg
A single-chain peptide analog of relaxin (H2) studied for anti-fibrotic effects in heart, lung and kidney research.
Mechanism of action
Functionally selective agonism of the RXFP1 relaxin receptor, biasing toward anti-fibrotic ERK signaling.
Research peptide — not approved. Like relaxin it is short-acting; human PK is not established, so the half-life here is an estimate.
References
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