PT-141 (Bremelanotide)
Also known as Bremelanotide, Vyleesi
PT-141 (Bremelanotide) is an approved on-demand injection (Vyleesi) for low sexual desire — it works through the brain rather than blood flow.
How one dose clears
modeled over ~6 half-lives- Half-life
- 2.7 h
- Time to peak (Tmax)
- 1.0 h
- Bioavailability
- 100%
- Typical dose
- 1.75 mg
Melanocortin receptor agonist FDA-approved (Vyleesi) for hypoactive sexual desire disorder.
Mechanism of action
Activates central melanocortin receptors (MC4R) influencing sexual response.
Can transiently raise blood pressure and cause nausea/flushing.
References
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