Pemvidutide
Also known as ALT-801
One-dose burn-down
Half-life
5.0 days
Tmax
2.0 days
Steady state
~35d
Typical dose
1.2 mg
Investigational albumin-binding GLP-1/glucagon dual receptor agonist for obesity and MASH, designed for once-weekly subcutaneous dosing.
Mechanism of action
A C18-diacid linker binds albumin to extend half-life; balanced GLP-1/glucagon agonism drives weight loss and hepatic-fat reduction.
Investigational — not approved. Once-weekly dosing implies a multi-day half-life; an exact human value is not publicly detailed, so the half-life here is an estimate.
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