Relamorelin
Also known as RM-131, BIM-28131
One-dose burn-down
Half-life
1.5 h
Tmax
30 min
Typical dose
100 mcg
Investigational ghrelin (GHS-R) receptor agonist studied for diabetic gastroparesis and constipation, accelerating gastric emptying.
Mechanism of action
Potent, stabilized ghrelin-receptor agonism stimulates GI motility (and GH release) with greater potency and longer duration than native ghrelin.
Investigational — not approved. More stable than ghrelin but still short-acting; a precise human half-life is not well published, so the value here is an estimate.
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