MK-677 (Ibutamoren)
Also known as Ibutamoren, MK-0677
MK-677 (Ibutamoren) is a once-daily pill that mimics the hunger hormone ghrelin to keep your growth hormone and IGF-1 elevated. It commonly increases appetite and water retention.
How one dose clears
modeled over ~6 half-lives- Half-life
- 24 h
- Time to peak (Tmax)
- 1.0 h
- Bioavailability
- 60%
- Steady state
- ~5 days
- Typical dose
- 25 mg
Orally active, long-acting ghrelin mimetic / GH secretagogue. Once daily.
Mechanism of action
Non-peptide GHS-R agonist that sustains GH and IGF-1 elevations with daily oral dosing.
Research compound — not FDA approved. Can raise appetite, blood glucose, and water retention.
References
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