Somatropin (HGH)
Also known as rhGH, Human Growth Hormone
Somatropin is lab-made human growth hormone (HGH), approved to treat growth-hormone deficiency. It supports growth, muscle, and tissue repair.
How one dose clears
modeled over ~6 half-lives- Half-life
- 3.0 h
- Reported range
- 2.5 h–4.0 h
- Time to peak (Tmax)
- 4.0 h
- Bioavailability
- 75%
- Steady state
- ~1 days
- Typical dose
- 2 IU
Recombinant human growth hormone, FDA-approved for GH deficiency and other indications.
Mechanism of action
Directly activates GH receptors and stimulates hepatic IGF-1; subcutaneous absorption limits the apparent half-life.
Prescription hormone. Plasma half-life is short but biological (IGF-1) effects persist far longer than blood levels suggest.
References
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