Semaglutide reconstitution calculator
Also known as Ozempic, Wegovy, Rybelsus
Reconstitute Semaglutide by adding bacteriostatic water to the vial, then draw your dose on a U-100 insulin syringe. The calculator is pre-filled with commonly-referenced vial sizes (2, 5, 10 mg) and water volumes (1, 2, 3 mL) — every field is yours to override. Once-weekly GLP-1 receptor agonist. A long ~7-day half-life means levels accumulate over several weeks to steady state.
New to this? How to use the calculator
- 1Enter what's on your vial. Type the peptide amount (mg) printed on the vial and the mL of bacteriostatic water you mixed in. Not sure how much water to add? Switch to the Solve: water tab and it tells you.
- 2Enter your dose — mind the unit. Type your target dose and pick mg or mcg with the toggle. This matters: 1 mg = 1000 mcg. GLP-1s (semaglutide, tirzepatide) are usually mg; most peptides (BPC-157, ipamorelin) are mcg.
- 3Read “Draw to … units”. The big number is how far to pull the plunger on a U-100 insulin syringe. Match it to the fill line on the syringe picture. The concentration and doses per vial are shown so a wrong answer looks wrong.
Three ways to use it: Solve: units (you have a dose, find the draw), Solve: water (you want a clean mark like 10 units, find the water), and Solve: dose (you drew some units, find the dose).
Full step-by-step guideI have a vial, water and a dose — how many units do I draw?
Want this protocol tracked, scheduled and burned down by half-life?
Track this protocolThis tool computes volumes only — it does not recommend doses. Any pre-filled values are commonly-referenced examples to confirm with your provider. Always verify the concentration and draw against your own vial and syringe.
Semaglutide concentration quick-reference
| Vial | BAC water | Concentration | Units for 0.25 mg |
|---|---|---|---|
| 2 mg | 1 mL | 2 mg/mL | 12.5 u |
| 2 mg | 2 mL | 1 mg/mL | 25 u |
| 2 mg | 3 mL | 0.667 mg/mL | 37.5 u |
| 5 mg | 1 mL | 5 mg/mL | 5 u |
| 5 mg | 2 mL | 2.5 mg/mL | 10 u |
| 5 mg | 3 mL | 1.67 mg/mL | 15 u |
| 10 mg | 1 mL | 10 mg/mL | 2.5 u |
| 10 mg | 2 mL | 5 mg/mL | 5 u |
| 10 mg | 3 mL | 3.33 mg/mL | 7.5 u |
Example inputs for illustration. Confirm your actual dose with your provider.
Semaglutide has a reported half-life of about 7.0 days. Track how much stays active between doses with a real pharmacokinetic burn-down.
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