How much bacteriostatic water do you add to a 5 mg Pramlintide (Symlin) vial?

A common choice is 1 mL, giving a concentration of 5 mg/mL. The exact volume is up to you — more water makes a more dilute, easier-to-measure solution. Use the calculator above to match your target dose to a clean syringe mark.

How many units of Pramlintide (Symlin) do I draw for a 60 mcg dose?

With a 5 mg vial in 1 mL of BAC water, a 60 mcg dose is 1.2 units on a U-100 insulin syringe.

Amylin analog

Pramlintide (Symlin) reconstitution calculator

Also known as Symlin

Reconstitute Pramlintide (Symlin) by adding bacteriostatic water to the vial, then draw your dose on a U-100 insulin syringe. The calculator is pre-filled with commonly-referenced vial sizes (5, 10 mg) and water volumes (1, 2 mL) — every field is yours to override. Amylin analog dosed before meals in micrograms — mind the mg/mcg distinction. The approved Symlin form is a pre-filled pen.

New to this? How to use the calculator

1Enter what's on your vial. Type the peptide amount (mg) printed on the vial and the mL of bacteriostatic water you mixed in. Not sure how much water to add? Switch to the Solve: water tab and it tells you.
2Enter your dose — mind the unit. Type your target dose and pick mg or mcg with the toggle. This matters: 1 mg = 1000 mcg. GLP-1s (semaglutide, tirzepatide) are usually mg; most peptides (BPC-157, ipamorelin) are mcg.
3Read “Draw to … units”. The big number is how far to pull the plunger on a U-100 insulin syringe. Match it to the fill line on the syringe picture. The concentration and doses per vial are shown so a wrong answer looks wrong.

Three ways to use it

Solve: units — you know the dose; find how far to draw.
Solve: water — you want a round mark like 10 units; find how much water to add.
Solve: dose — you already drew some units; find the dose that was.

Full step-by-step guide

I have a vial, water and a dose — how many units do I draw?

Peptide in the vialmgThe amount printed on the vial label.BAC water addedmLBacteriostatic water you mixed in.

Target dose

Check the unit: 1 mg = 1000 mcg.

Syringe size

U-100 insulin syringe — 1 mL holds 100 units.

Vial cost (optional)$Adds a cost per dose.

Draw to

1.2 units

Concentration: 5 mg/mL
Volume per dose: 0.012 mL
Doses per vial: 83.33

Only 1.2 units — that's hard to measure accurately on a U-100 syringe. Add less BAC water for a larger, easier-to-read volume (try "Solve: water").

A U-100 syringe is marked in whole units. The nearest mark is 1 units, which delivers 50 mcg (your target is 60 mcg) — that's 17% off. Adding more water spreads the dose over more units so it's easier to measure.

Want this dose scheduled, checked off daily and tracked by half-life?

Track it for free

This tool computes volumes only — it does not recommend doses. Any pre-filled values are commonly referenced examples to confirm with your provider. Always check the concentration and draw against your own vial and syringe.

Pramlintide (Symlin) concentration quick-reference

Vial	BAC water	Concentration	Units for 60 mcg
5 mg	1 mL	5 mg/mL	1.2 units
5 mg	2 mL	2.5 mg/mL	2.4 units
10 mg	1 mL	10 mg/mL	0.6 units
10 mg	2 mL	5 mg/mL	1.2 units

Example inputs for illustration. Confirm your actual dose with your provider.

Pramlintide (Symlin) has a reported half-life of about 48 min. Track how much stays active between doses with a real pharmacokinetic burn-down.

Track Pramlintide (Symlin) in PeptideBuddy

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